Andrew Pambrun was born at Cumberland House near the mouth of the Sasketchewan River in 1821. He attended school at Fort Vancouver in 1832 and then at Red River School in Manitoba where he stayed and taught for six years. Andrew returned to Oregon in 1850 and later worked for Hudson's Bay Co. at Fort Walla Walla. From 1855 to 1858 he served as an aide to territorial governor Isaac Stevens and was of great service during the negotiation of the Treaties of 1855. Pambrun continued to live in the Walla Walla area until his death.

Andrew is portrayed by his great grandson, Sam Pambrun, local historian, teacher and past president of the Umatilla Historical Society. The Pambrun family has lived in this area continuously since the 1830s.